Cruz won't play Sunday against the 49ers, but is aiming to return for the Giants' Week 6 outing at Philadelphia on Oct. 19, Ralph Vacchiano of the New York Daily News reports.

Cruz is slated for an examination with team doctors Monday, which is 10 days removed from receiving a PRP injection in his left calf, after which he'll recalibrate his timetable for a return to running, according to Art Stapleton of The Record. With a Monday night contest in Week 6, Cruz will have an extra day to prove the health of the calf, but next Thursday's practice will ultimately set the groundwork for his potential to make his season debut.

Cruz (calf) still has no timetable for a return, NJ.com reports.

Cruz is kicking off Week 5 preparation with a no-show at Wednesday's practice, and until he returns to drills, his season debut will continue to be delayed. In Cruz's absence, Eli Manning has been working with favored target Odell Beckham, with Larry Donnell and Reuben Randle acting as secondary options in the Giants' passing attack.

Cruz had a platelet-rich plasma (PRP) injection Thursday in an effort to help his injured calf, Art Stapleton of The Record reports.

Cruz was expected to play this week after missing the first three weeks of the season, however a setback during Wednesday's practice has now put his status for upcoming weeks in limbo, with no timetable in sight. While this PRP procedure should help Cruz regain strength in his injured left calf strain quicker, there isn't concrete evidence to suggest when he will be able to return to the field. In his absence, Odell Beckham and Rueben Randle will continue to see the majority of the targets at receiver.

Coach Tom Coughlin acknowledged Thursday that at this stage there is no timetable for the return of Cruz, who aggravated his left calf injury at practice on Wednesday.

While the Giants aren't inclined to estimate when Cruz might return to action, ESPN's Dan Graziano speculated Wednesday that it could be several weeks before the wideout is finally able to suit up. In the meantime, Odell Beckham and Reuben Randle will continue to head the Giants' wideout corps and it's possible that the team could elect to add depth at the position in the wake of Cruz's recent injury setback.

Cruz (calf) has officially been ruled out for Week 4, Josina Anderson of ESPN reports.

Initially expected to make his season debut Sunday, Cruz suffered a setback during Wednesday's practice and will continue to be sidelined. Odell Beckham remains the Giants' clear No. 1 receiver, with Reuben Randle and Dwayne Harris slotting in as the second and third options in Cruz's continued absence.

Cruz suffered a setback with his left calf at Wednesday's practice, Art Stapleton of The Record reports. According to head coach Tom Coughlin, "Victor came out and tried to do individuals. He felt the calf again and that's all he did."

Cruz was expected to ramp up his workload this week in anticipation of taking the field Sunday in Buffalo, but Wednesday's tweak puts a damper on those plans. If he sits out again, Eli Manning will still have Odell Beckham, Rueben Randle, and Dwayne Harris at his disposal.

Cruz (calf) will practice Wednesday, Art Stapleton of The Record reports.

It's not clear how much work Cruz will get in during the Giants' first official practice of the week, but his participation alone in Wednesday's session keeps the momentum moving toward him making his season debut in Week 4.

Cruz (calf) returned to practice Monday, The Record reports.

Cruz has been targeting a return to action in Week 4, so his participation in Monday's practice certainly seems to suggest that timetable is going as planned. While it will be interesting to monitor his activity level throughout the week, it appears Cruz has a good chance of making his season debut this weekend against the Bills.

Cruz (calf) said he will return for Week 4 against the Bills, the New York Daily News reports.

Although Week 4 has been the realistic target for quite some time, Cruz's presence shouldn't be assumed, as he still hasn't returned to practice. He has been running and cutting on his own since Tuesday, and he sounds confident about his ability to suit up for Week 4.

Cruz (calf) has been ruled out for Thursday's game against Washington.

The expectation all along has been a return in Week 4, so imminent inactive status is no surprise. He took a huge first step in his goal Tuesday, when he ran and cut on grass for the first time since spraining his left calf in mid-August. With continued progress, he could very well make his season debut on Oct. 4 in Buffalo.

Cruz ran and cut on grass Thursday for the first time since he sprained his left calf in mid-August, the Newark Star-Ledger reports.

Cruz said he'd lobby coach Tom Coughlin to play Thursday against the Redskins, but didn't seem optimistic Coughlin would give him the green light. How Cruz fares in Wednesday's practice should give us a better idea of his chances.

Cruz (calf) said he will need a lot of improvement in the next two days to have any shot at playing against the Redskins on Thursday, Ralph Vacchiano of the New York Daily News reports.

Although he didn't take part in Tuesday's practice, Cruz did show some signs of improvement, running full speed in agility drills off to the side, according to Art Stapleton of The Record. Cruz does seem to be in good shape for a Week 4 return, but the short turnaround leaves him unlikely to be ready for Thursday against the Redskins.

Cruz (calf) will not practice Tuesday, Art Stapleton of The Record reports.

Cruz will remain sidelined with his calf injury Tuesday, likely dashing any hopes of him suiting up in Week 3 with game day just two days away. He has yet to practice this season, and will almost certainly have to do so before he is cleared for game action.

Cruz (calf) wouldn't have participated Monday, if the Giants had held practice, Ralph Vacchiano of the New York Daily News reports.

With another absence expected Thursday against Washington, any practice reps Cruz fits in this week should be viewed as a significant development. In his stead, the Giants will continue to rely upon Rueben Randle and Preston Parker next to clear-cut No. 1 wideout Odell Beckham.

Cruz (calf) is out for Sunday's game against the Falcons, Newsday's Tom Rock reports.

Cruz has yet to practice through the first two weeks of the season, with recent reports suggesting he may not be ready until Week 4. Rueben Randle will start across from Odell Beckham against the Falcons, leaving Preston Parker as the No. 3 wide receiver.

Cruz (calf) will not practice Thursday, Ralph Vacchiano of the New York Daily News reports.

Cruz continues to nurse a calf injury that's plagued him throughout camp, and it appears imminent that he'll remain sidelined for Week 2, and possibly beyond. While coach Tom Coughlin has characterized Cruz's injury as "minor," reports Wednesday suggested that Cruz may not make his return until Week 4. That means Reuben Randle and Preston Parker will continue to serve as the No. 2 and 3 receivers behind Odell Beckham, Jr.

Jordan Raanan of NJ.com suggests that Cruz (calf) may not return until Week 4.

During another idle practice Wednesday, Cruz didn't run in the portion open to the media, meaning he hasn't participated in that simple activity in more than a month. Until he does so, he'll be a shoe-in for inactive status come game day, even if head coach Tom Coughlin has termed Cruz's calf concern as "minor" in the past. The schedule doesn't lend itself to an imminent return -- after taking the field Sunday against the Falcons, the Giants have a quick turnaround, with a game next Thursday versus Washington -- which likely guided Raanan's assumption that a season debut in Week 4 is Cruz's best-case scenario.

Cruz (calf) will not practice Wednesday, Ralph Vacchiano of the New York Daily News reports.

Cruz has been hampered by a calf injury which has limited him since mid-August, however coach Tom Coughlin made a point of describing the injury as "just a strain". It's unclear at this time when Cruz might return to the practice field, but his absence could create more opportunities for Preston Parker and Rueben Randle.

Cruz (calf) is out for Sunday's game against the Cowboys.

Considered a longshot to play, Cruz was a non-participant in practice all week. With the Giants' first three games coming in a span of just 12 days, there's been speculation that Cruz may not be available until Week 4. In his absence, Preston Parker will likely serve as the No. 3 wide receiver.

Cruz (calf) didn't practice Thursday, but head coach Tom Coughlin won't rule out the wide receiver for Sunday night's outing at Dallas.

The Giants' early-season schedule includes games on Sept. 13, 20, and 24, which doesn't lend itself to an ailing player like Cruz. Moreover, Thursday's practice was the team's final full one in advance of Sunday's contest, meaning the wideout would be hard-pressed to display his health in a walkthrough. All signs are pointing to an absence in Week 1, at the very least, which could be confirmed upon the release of Friday's injury report.